Watch Intently (1)phenobarbital will decrease the level or result of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers may lead to some lessen in fentanyl plasma concentrations, not enough efficacy or, quite possibly, progress of a withd… Read More